The Good, The Bad and Drug Shortages.

It doesn’t take a rocket scientist to know that when you don’t have enough of a good thing, bad things can happen. This is the case with the on-going drug shortages and the resulting potential issues that affect the care we provide and patient safety concerns. The ISMP (Institute for Safe Medication Practices) recently released…

Epogen and Procrit: Voluntary Recall

Certain lots of Epogen and Procrit (Epoetin alfa) vials are being recalled as a precaution, because the vials may contain extremely thin glass flakes (lamellae) that are barely visible. The potential serious adverse events resulting from the use of a sterile injectable product with particulates by the intravenous route include embolic, thrombotic and other vascular…

FDA Class I Recall: Symbiq Infusion Pumps

There is an FDA Class I recall of Symbig Infusion Pumps One channel, model 16026 and Dual channels, model 16027 made by Hospira due to the potential for unrestricted flow of fluid or medication if the administration set (cassette) is removed before the cassette carriage fully opens and the slide/roller clamp is not closed. Additionally,…

Vesicants: not just chemo agents!

There is no doubt that several chemotherapeutic agents have vesicant properties, and when inadvertently infused into the surrounding tissue from an infiltrated IV, these agents may have the potential to cause blisters, severe tissue injury or necrosis, known as extravasation. The damage to the tissue can occur from direct contact with the vesicant medication, from…

2010 NIOSH List Antineoplastic/Hazardous Drugs

The National Institute of Occupational Safety and Health (NIOSH) released an update to the 2004 sample list of hazardous drugs. The 2010 list supersedes the 2004 list and includes 21 additional drugs.  According to ASHP [1990] the definition of hazardous drugs:1. Carcinogenicity 2. Teratogenicity or other developmental toxicity 3. Reproductive toxicity4. Organ toxicity at low…

Overheard in an Infusion Center….

“ we’re just like a filling station, they (patients) come here, we fill them up and let them go”!! This was the response from several RN’s working in a hospital based outpatient infusion center I recently visited where chemotherapy and biologic agents are administered to patients with oncologic and non-oncologic disorders, including patient’s with immune…

Multi-dose vials….not forever!!

Unlike the “Forever” stamps from the US Post Office, we should not keep using multi-dose vials until the vial is empty. Multi-dose vials are  to be discarded 28 days after first use, unless the manufacturer specifies otherwise (shorter or longer), according to the Joint Commission Medication Management Standards FAQ about multi-dose vials. So you say,…